【新产品】安必奇生物供应新型冠状病毒科研用ACE2蛋白-商家动态-资讯-生物在线

【新产品】安必奇生物供应新型冠状病毒科研用ACE2蛋白

作者:北京安必奇生物科技有限公司 2020-02-06T10:38 (访问量:16888)

新型冠状病毒科研试剂

为了支持武汉新型冠状病毒相关研究和治疗产品开发,安必奇生物成立了专项工作小组,开展新型冠状病毒的研究。我们很快拿到了病毒基因序列信息,并研发生产出新型冠状病毒主要受体-ACE2蛋白产品,用于新型冠状病毒科学研究。

ACE2蛋白产品:

  • ACE2-239H (Fc region of human IgG1)
  • ACE2-185H (Fc region of mouse IgG1)
  • ACE2-736H

同时,我们正在积极制备2019-nCoV S1蛋白,届时可与ACE2蛋白配套供应。我们密切关注新型冠状病毒研究动态,逐步提供更多科研试剂满足新型冠状病毒研究。

产品信息:

产品名称

Recombinant Human ACE2, Fc tagged

货号

ACE2-239H

产品信息

Recombinant Human ACE2 extracellular domain precursor (Met 1-Ser 740) (NP_068576.1), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell.

来源

Human cells

成分

Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5

分子量

The recombinant human ACE2/Fc is a disulfide-linked homodimeric protein. The reduced monomer consists of 961 amino acids and predicts a molecular mass of 110.3 kDa. As a result of glycosylation, the rhACE2/Fc monomer migrates as approximately 145-150 kDa band in SDS-PAGE under reducing conditions.

内毒素

< 1.0 eu per μg of the protein as determined by the LAL method

纯度

>90 % as determined by SDS-PAGE

 

产品名称

Recombinant Human ACE2 Protein, Fc-tagged

货号

ACE2-185H

产品信息

Recombinant human ACE2 (NP_068576.1) (Met1-Ser740) was expressed with the Fc region of mouse IgG1 at the C-terminus.

来源

HEK293

成分

Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol

分子量

The recombinant human ACE2 consists 957 amino acids and predicts a molecular mass of 110 kDa.

内毒素

< 1.0 EU per μg of the protein as determined by the LAL method

纯度

>90 % as determined by SDS-PAGE

 

产品名称

Recombinant Human ACE2, His-tagged

货号

ACE2-736H

产品信息

Recombinant human ACE-2 produced by transfected human cells is a secreted protein with sequence (Gln18-Ser740) of human ACE-2 fused with a polyhistidine tag at the C-terminus.

来源

HEK293

成分

Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, 0.1mM ZnCl2, 10% Glycerol, pH 7.5

生物活性

Specific Activity is > 800 pmol/min/μg as measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH

内毒素

Less than 0.1 ng/μg (1 IEU/μg)

纯度

Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE

 
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