ABCG4,ABC膜转运蛋白抗体

产品编号HZ-1727R
英文名称ABCG4
中文名称ABC膜转运蛋白抗体
别 名ATP binding cassette, subfamily G member 4; ABCG 4; ATP binding cassette subfamily G member 4; WHITE 2; WHITE2; ABCG4_HUMAN.
规格价格0.1ml 0.2ml
说 明 书0.1ml 0.2ml
研究领域免疫学 神经生物学 转运蛋白 细胞表面分子
抗体来源Rabbit
克隆类型Polyclonal
ABCG4,ABC膜转运蛋白抗体交叉反应Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量71kDa
细胞定位细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human ABCG4
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
ABCG4,ABC膜转运蛋白抗体PubMedPubMed
产品介绍background:
he ATP binding cassette (ABC) superfamily of membrane transporters is one of the largest protein classes known, and counts for numerous proteins involved in trafficking of biological molecules across membranes. ABCG4 protein is highly expressed in both human and mouse brain, it is a 646aa molecule in human (chr 11q23) and mouse. It is an integral membrane protein may be involved in macrophage lipid homeostasis. The ABCG4 protein’s abundant expression in brain and close evolutionary relationship to the other members of the subfamily suggests a potential role in cholesterol transport.

Function:
May be involved in macrophage lipid homeostasis.

Subcellular Location:
Membrane; Multi-pass membrane protein (Probable).

Similarity:
Belongs to the ABC transporter superfamily. ABCG family. Eye pigment precursor importer (TC 3.A.1.204) subfamily.
Contains 1 ABC transmembrane type-2 domain.
Contains 1 ABC transporter domain.

Gene ID:
64137

ABCG4,ABC膜转运蛋白抗体Database links:
Entrez Gene: 64137 Human
Entrez Gene: 192663 Mouse
Entrez Gene: 300664 Rat
Omim: 607784 Human
SwissProt: Q9H172 Human
Unigene: 126378 Human
Unigene: 101876 Mouse
Unigene: 29008 Rat

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.