TFEC 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
TFEC 抗体

TFEC 抗体

商家询价

产品名称： TFEC 抗体

英文名称： TFEC Antibody

产品编号： XY 13547-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
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 TFEC 抗体Applications

In-house applications ELISA, WB, IHC, IP     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
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  • 13547-1-AP;mouse testis tissuemouse testis tissue were subjected to SDS PAGE followed by western blot with 13547-1-AP(TFEC antibody) at dilution of 1:300
  • 13547-1-AP;Colon cancerImmunohistochemical of paraffin-embedded human colon cancer using 13547-1-AP(TFEC antibody) at dilution of 1:100 (under 10x lens)
  • 13547-1-AP;Colon cancerImmunohistochemical of paraffin-embedded human colon cancer using 13547-1-AP(TFEC antibody) at dilution of 1:100 (under 40x lens)
  • 13547-1-AP;mouse testis tissueIP Result of anti-TFEC (IP:13547-1-AP, 4ug; Detection:13547-1-AP 1:500) with mouse testis tissue lysate 4000ug.
Positive WB detected in Mouse testis tissue, COLO 320 cells
Positive IP detected in Mouse testis tissue
Positive IHC detected in Human colon cancer tissue
Recommended dilution WB : 1:500-1:5000
IP : 1:200-1:2000
IHC : 1:20-1:200
 TFEC 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information TFEC 抗体
Immunogen TFEC fusion protein ag4061 Full name Transcription factor EC
Calculated molecular
weight		 347aa,39 kDa Observed molecular 
weight		 65 kDa
GenBank accession 
number		 BC029891 Gene ID (NCBI) 22797
Gene symbol TFEC Synonyms BHLHe34, hTFEC L, TCFEC, TFE C, TFEC, TFECL, transcription factor EC, Transcription factor EC like
Background

The DNA-binding factor TFE3 contains adjacent helix-loop-helix (HLH) and leucine zipper (LZ) domains flanked by an upstream basic region. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. TFE3 is ubiquitously expressed and can directly associate with DNA as either homodimers or heterodimers formed with two related proteins, TFEB or TFEC. TFE3 binds to and activates the microE3 motif of the immunoglobulin heavy-chain enhancer to induce B cell-specific gene transcription and DNA recombination. TFEC shares a bHLH/LZ structure with TFE3 and a closely related protein microphthalmia-associated transcription factor (MITF), which is critically involved in melanocyte differentiation. Unlike TFE3, the expression of TFEC is largely restricted to fibroblasts, myoblasts, chondrosarcoma cells and myeloma cells. TFEC 抗体

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