RAB6B,RAS癌基因相关蛋白RAB6B抗体

产品编号HZ-8307R
英文名称RAB6B
中文名称RAS癌基因相关蛋白RAB6B抗体
别 名RAB6B; RAB6B member RAS oncogene family; RAB6B_HUMAN; Ras related protein Rab 6B; Ras-related protein Rab-6B; Small GTP binding protein; Small GTPase RAB6B.
说 明 书0.1ml 0.2ml
研究领域肿瘤 细胞生物 免疫学 信号转导 G蛋白偶联受体 G蛋白信号
抗体来源Rabbit
克隆类型Polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit,
RAB6B,RAS癌基因相关蛋白RAB6B抗体产品应用WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量23kDa
细胞定位细胞浆 细胞膜
性 状Lyophilized or Liquid
浓 度1mg/1ml
免 疫 原KLH conjugated synthetic peptide derived from human RAB6B
亚 型IgG
纯化方法affinity purified by Protein A
储 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
RAB6B,RAS癌基因相关蛋白RAB6B抗体PubMedPubMed
产品介绍background:
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.

Function:
Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells.

Subunit:
Interacts with CCDC64/BICDR1; leads to its accumulation in the pericentrosomal region (By similarity). Interacts with RAB6KIFL. Interacts (GTP-bound) with BICD1 (via C-terminus); the interaction is direct. Interacts (GDP-bound) with DYNLRB1.

Subcellular Location:
Golgi apparatus membrane. Cytoplasmic vesicle. Colocalizes with BICD1 at vesicular structures that align along microtubules.

Tissue Specificity:
Predominantly expressed in brain.

Similarity:
Belongs to the small GTPase superfamily. Rab family.

RAB6B,RAS癌基因相关蛋白RAB6B抗体Database links:
UniProtKB/Swiss-Prot: Q9NRW1.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.